Lung caner
Conditions
Interventions
control group:Pemetrexed combined with cisplatin chemotherapy, PD-1 monoclonal antibody, bevacizumab
Experimental group:On the basis of the control group the experimental group was given a traditional Chinese medicine formula based on Shamaidong Tang at the same time orally for two weeks stopped for
Sponsors
Jinshazhou Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: a. Pathologically diagnosed as lung adenocarcinoma with distant metastasis; b. EGFR wild-type and ALK negative; c. Traditional Chinese medicine syndrome differentiation is characterized by deficiency of both qi and yin: fatigue and weakness in the mind dry mouth and insufficient drinking red or pale tongue and weak pulse; d. Age range from 18 to 80 years old (including 18 and 80 years old) regardless of gender; e. The expected survival period exceeds three months; f. No previous use of pemetrexed combined with cisplatin chemotherapy and currently suitable for this chemotherapy regimen; g. ECOG score = 2 points; h. Sign an informed consent form
Exclusion criteria
Exclusion criteria: a. Existence of brain metastasis; b. Severe liver and kidney dysfunction (Child C liver function stage 4-5 kidney disease); c. Application of other immune preparations; d. Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| INF-?;T lymphocyte subpopulation; | — |
Secondary
| Measure | Time frame |
|---|---|
| PFS(Progression Free Survival);Adverse reactions; | — |
Countries
China
Contacts
Public ContactXiang Li
Jinshazhou Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed