Diminished ovarian reserve
Conditions
Interventions
Control group:Drug therapy of complex packing estradiol tablets/estradiol and dydrogesterone tablets
Experimental group:Warming Needle Moxibustion at Zhongji and Guanyuan Points
Sponsors
Shanghai Research Institute of Acupuncture and Meridian
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Women aged ranged from 18 to 40 years old; 2. Meet the western diagnostic criteria for diminished ovarian reserve 10mlU/ml < follicle stimulating hormone (FSH) < 25 mlU/ml and antimullerian hormone (AMH) < 1.1 ng/ml; 3. Understand and agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Those with ophorectomy hysterectomy ovarian tumors or those with combined organic lesions of the reproductive organs; 2. Those who have combined serious primary diseases such as cardiovascular cerebrovascular hepatic renal and hematopoietic systems or those who suffer from non-serious diseases but need to be maintained with medication; 3. Pregnant or lactating women or female patients who have recently prepared for pregnancy; 4. Those who applied hormonal or immunosuppressive drug therapy within 3 months prior to participation in this study; 5.Those with known contraindications to acupuncture treatment such as having spontaneous bleeding or bleeding that does not stop after an injury having infections ulcers or tumors on the skin or those with a known drug allergy to complex packing estradiol tablets/estradiol and dydrogesterone tablets; 6. Those who have participated or are participating in other clinical trials within 1 month prior to participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Follicle stimulating hormone (FSH); | — |
Secondary
| Measure | Time frame |
|---|---|
| Prolactin (P);Ultrasound of uterus and adnexa;Testosterone (T);Estradiol(E2);Antimullerian hormone (AMH);Syndrome score;Progesterone (P);Luteinizing hormone (LH);Menstrual score; | — |
Countries
China
Contacts
Public ContactXu Mingshu
Shanghai Research Institute of Acupuncture and Meridian
Outcome results
None listed