Chronic hand eczema
Conditions
Interventions
Control group:Moisturizing and anti-itching wash placebo (granules) + mometasone furoate cream
Treatment group:Moisturizing and anti-itching wash (granules) + simulated mometasone furoate cream
Sponsors
Guang'anmen Hospital China Academy Of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for mild to moderate chronic hand eczema in the "Chinese Expert Consensus on the Diagnosis and Treatment of Hand Eczema (2021 Edition)" (HECSI score: =27). 2. Meets the diagnostic criteria for blood deficiency and wind-dry type chronic eczema in the "Expert Consensus on the Diagnosis and Treatment of Eczema" in Traditional Chinese Medicine (2021)". 3. Patients aged 18 to 70 years (inclusive) both male and female. 4. The primary affected area is both hands. 5. Informed consent has been obtained, and the patient is willing to adhere to the treatment.
Exclusion criteria
Exclusion criteria: 1. Patients with any systemic or active skin diseases (such as psoriasis) that may affect the evaluation of experimental results or with scars, tattoos, birthmarks, or other pigmented skin conditions at the affected site that could interfere with the assessment of skin lesions. 2. Patients with confirmed bacterial, viral, or fungal infections at the application site who require anti-infection treatment. 3. Patients with serious underlying diseases such as cardiovascular, cerebrovascular, liver, kidney, or hematologic system disorders, as well as those with mental disorders. 4. Patients who have used systemic corticosteroids or immunosuppressants within 30 days before treatment; patients who have received biologics or small-molecule drug treatments within 90 days; patients who have used topical corticosteroids or retinoid drugs within the past week. 5. Patients with a history of allergies to any components of the trial medication. 6. Pregnant or breastfeeding women or women who plan to conceive within the next three months. 7. Patients who have participated in other clinical drug trials in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS score;HECSI score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient Eczema Self-Assessment Score(POEM Score);Dermatology Life Quality Index (DLQI) Score;Rash area;IGA score; | — |
Countries
China
Contacts
Public ContactJiao YANG
Guang'anmen Hospital China Academy Of Chinese Medical Sciences
Outcome results
None listed