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Effect of invigorating spleen and clearing heat and activating blood circulation on improving chronic atrophic gastritis by regulating macrophage polarization through miR-632 targeting GSK-3ß

Effect of invigorating spleen and clearing heat and activating blood circulation on improving chronic atrophic gastritis by regulating macrophage polarization through miR-632 targeting GSK-3ß

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025000281
Enrollment
Unknown
Registered
2025-02-16
Start date
2025-02-20
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic atrophic gastritis

Interventions

pretreated group:invigorating spleen and clearing heat and activating blood circulation
nomal:none

Sponsors

First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ( Patients should meet the following criteria at the same time ) : 1 Meet the diagnostic criteria of chronic atrophic gastritis in western medicine ; 2 age greater than or equal to 18 years old ; 3 be able to communicate in Chinese and willing to accept treatment and follow-up.

Exclusion criteria

Exclusion criteria: ( meet any of the following criteria are excluded ) : 1 Patients with any other diseases that can explain the above clinical symptoms ; 2 patients with chronic esophagitis Barrett 's esophagus gastroesophageal reflux disease peptic ulcer polyposis gastrointestinal tumors ; 3 patients with severe gastric mucosal dysplasia pathological diagnosis of malignant transformation gastrointestinal organic diseases found by endoscopy ; patients with a history of abdominal surgery ; 5 Allergic constitution or allergies to a variety of drugs ; 6 patients with unconsciousness dementia various mental diseases severe neurosis and unwilling to cooperate ; 7 patients with cardiovascular and cerebrovascular diseases renal insufficiency hematopoietic system and other serious primary diseases ; 8 pregnant and lactating women ; 9 Cognitive or other impairments ( such as vision ) that affect participants to complete self-reports ; 10 Investigators have good reason to believe that it is not suitable for researchers based on the current medical or psychological state of the participants.

Design outcomes

Primary

MeasureTime frame
abdominal pain score;

Countries

China

Contacts

Public ContactZhuangkunhai

First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine

sea-zhuang007@163.com13580420597

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026