Parkinson's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Meet the diagnostic criteria for PD and PD-FOG; Patients with PD-FOG of liver and kidney deficiency type and phlegm and stasis obstruction type; Hoehn-Yahr classification = stage 2; Able to communicate and interact effectively; Receiving anti-PD drug therapy with stable dose for at least 30d; All patients were required to sign an informed consent form before participating in the study.
Exclusion criteria
Exclusion criteria: The existence of skin breakage coagulation dysfunction and other contraindications to gua sha; Those with combined severe cardiac pulmonary hepatic renal and haematopoietic system diseases or malignant tumours mental disorders; Those who participate in other clinical trials during the intervention period; Presence of adverse reactions such as unpredictable drug fluctuations; Those with secondary Parkinson's syndrome and Parkinson's superimposed syndrome; Those with other medical conditions that affect the ability to walk; Patients who have undergone deep brain electrical stimulation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| New Freezing of Gait Questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| Substantia Nigra Pars Compacta Dopaminergic Neuron;High Sensitivity C-Reactive Protein;Locus Coeruleus Norepinephrine Neuron;functional connectivity of brain areas;intracerebral structures;ReadyGo Quantitative Motor Function Evaluation System;Berg Balance Scale;Parkinson's Disease Questionaire-39;uric acid;Timed Up and Go Test;Uni?ed Parkinsons disease rating scale-?; | — |
Countries
China
Contacts
Changshu Hospital of Traditional Chinese Medicine