Ischemic stroke
Conditions
Interventions
Disease Registry Group:not have
Pushen Capsules Group:4 capsules/time 3 times/day
Sponsors
Drum Tower Hospital Affiliated to Nanjing University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients admitted to the hospital who were diagnosed as ischemic stroke (in line with the diagnostic criteria for ischemic stroke in the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018) and those who met the TOAST were diagnosed as Large artery atherosclerosis (LAA); (2) Patients who have been ill for less than 7 days; (3) Patients give informed consent to the study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) History of cerebral hemorrhage or hemorrhagic cerebrovascular disease (diagnosed by head CT/MRI including subarachnoid hemorrhage cerebral hemorrhage and other intracranial hemorrhage) within the past six months; (2) Confirmed through examination that cerebral embolism is caused by brain tumors traumatic brain injury cerebral parasitic diseases metabolic disorders rheumatic heart disease coronary heart disease and other heart diseases combined with atrial fibrillation and thrombus detachment as well as patients of unknown etiology; (3) Diabetes complications (such as severe diabetes nephropathy leading to renal insufficiency diabetes peripheral neuropathy affecting patients' motor function evaluation diabetes ketoacidosis etc.) and recurrent hypoglycemia; (4) Patients with severe malnutrition and severe blood diseases (such as hypoalbuminemia severe anemia etc.) and severe electrolyte imbalances that cannot be corrected through treatment; (5) Patients with severe cardiovascular and pulmonary diseases as w
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of subjects with mRS scores ranging from 0 to 2 after 12 weeks of treatment.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Has the mRS score decreased to 0-1 points;The change value and rate of NIHSS score;Whether cardiovascular and cerebrovascular events occur (stroke myocardial infarction TIA death etc.);The change value and rate of change in the Montreal Cognitive Assessment Scale (MoCA) score;The change value and rate of TCM symptom score;mRS score improvement rate;The change value and rate of the Mini Mental State Examination (MMSE) score;Changes in Four Blood Lipids; | — |
Countries
China
Contacts
Public ContactXu Yun
Nanjing Gulou Hospital
Outcome results
None listed