Acute Ischemic Stroke
Conditions
Interventions
Control group:Oral administration of placebo for 14 days in addition to conventional Western medicine treatment.
Intervention group:Oral administration of XifengTongluo formula granules for 14 days in addition to conventional Western medicine treatment.
Sponsors
Dongfang Hospital Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) AIS patients who meet the indications for thrombolysis and have received intravenous thrombolysis; (2) Patients who meet the diagnostic criteria for the syndrome of "Liver Yang Rising and Wind Causing Obstruction Blood Stasis in the Brain Collaterals" in stroke; (3) Patients with no change in NIHSS score or an increase of =1 point in NIHSS score within 72 hours after thrombolysis; (4) GCS score =12; (5) 18 - 85 years; (6)Signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients who did not receive intravenous thrombolysis for various reasons; (2) Receive direct endovascular thrombectomy or subsequent endovascular bridging interventions; (3) Cerebral infarction due to cardiogenic causes; (4) With severe circulatory respiratory urinary or digestive system diseases or cancer; (5) With liver or kidney dysfunction with levels exceeding twice the normal value; (6) Pregnant or lactating women; (7) Patients with pre-existing mental disorders or severe aphasia agnosia or inability to communicate and who cannot cooperate with efficacy assessments; (8) Allergic to the herbal ingredients used in this study protocol; (9) Currently participating in other clinical trials; (10) Patients who cannot comply with the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| SSS score;mRS score;Traditional Chinese Medicine (TCM) syndrome score;ADL score;MoCA score; | — |
Countries
China
Contacts
Public ContactXianglan Jin
Dongfang Hospital of Beijing University of Chinese Medicine
Outcome results
None listed