Sick sinus syndrome
Conditions
Interventions
Control group:Basic treatment
Test group:Basic treatment and Lingbao Huxin Dan(Take after meals 4 pills 3 times a day)
Sponsors
Fuwai Hospital Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1)Age greater than 18 years old (including endpoint value) gender is not limited; (2)Sinus bradycardia or slow-fast syndrome that meets Western medical diagnostic criteria for sick sinus syndrome; (3)Meet the Chinese medicine diagnostic criteria for qi deficiency and blood stasis syndrome; (4)Understand and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1)Intracranial disease severe hypoxia hypothermia hypothyroidism obstructive jaundice and vasovagal syncope medications acute inferior myocardial infarction atrioventricular block double knots myocarditis ischemic heart disease and other causes of bradyarrhythmias; (2)Sinus node dysfunction caused by carotid sinus hypersensitivity cerebrovascular accident hyperkalemia vagus nerve tone etc. which inhibits sinus node function; (3)Those who have fainted due to severe bradycardia within 1 month; (4)Patients who are taking heart-rate-slowing medications such as ß adrenergic receptor blockers or non-dihydropyridine calcium channel blockers; (5)Those who plan to implant a pacemaker during the study period or have obvious indications for implantable pacemaker (if there are obvious symptoms caused by sinus node dysfunction); (6)Those who have serious heart liver kidney blood system nervous system and other diseases based on past and present medical history; (7)Patients who participated in other clinical trials within
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical efficacy overall effective rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| 24-hour dynamic electrocardiogram sinus rhythm fastest heart rate;Chinese medicine symptom score;24-hour dynamic electrocardiogram sinus rhythm slowest heart rate;Mean heart rate with sinus rhythm on 24 hours dynamic electrocardiogram.;Total duration of ectopic rhythms (including atrial flutter, atrial tachycardia, and atrial fibrillation) on 24-hour dynamic electrocardiogram;Cardiovascular event rate;Proportion of sinus rhythm duration on 24-hour dynamic electrocardiogram;Proportion of pacemaker implantation; | — |
Countries
China
Contacts
Public ContactYao Yan
Fuwai Hospital Chinese Academy of Medical Sciences
Outcome results
None listed