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Study on the role of damp-heat in colorectal cancer based on ctDNA methylation

Study on the role of damp-heat in colorectal cancer based on ctDNA methylation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025000240
Enrollment
Unknown
Registered
2025-02-12
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Spleen deficiency and dampness-stasis syndrome group:none
Qi stagnation and blood stasis syndrome group:none
Damp-heat accumulation syndrome group:none
Normal control group:none
Cold-dampness block syndrome group:none

Sponsors

Fujian Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) In line with the early diagnosis of colorectal cancer, the four diagnostic data of traditional Chinese medicine is complete without damage, and according to the four diagnostic data and clinical manifestations, the classification of TCM syndrome can be clearly diagnosed. (2) Age: 18-70 years old. (3) Sign informed consent and voluntarily participate in the trial.

Exclusion criteria

Exclusion criteria: (1) Pregnant and lactating women. (2) Under 18 years old or over 70 years old. (3) Patients with other serious primary diseases that cannot be treated by surgery, and/or psychiatric patients. (4) Patients who had undergone radiotherapy and chemotherapy, targeted therapy, endocrine therapy, and local resection. (5) enteroscopy for diagnosis of enteritis, intestinal ulcer and other types of intestinal diseases. (6) There are contraindications to colonoscopy, failure to complete a total colon examination, or bowel examination

Design outcomes

Primary

MeasureTime frame
CEA;ctDNA;CA199;

Secondary

MeasureTime frame
Stool routine;urinalysis;Liver function;Fecal FIT-DNA;renal function;

Countries

China

Contacts

Public ContactXiaoyan Fu

Fujian Second People's Hospital

505334748@qq.com13859021863

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026