Acute ischemic stroke
Conditions
Interventions
Control group:Standardized Western Medicine Treatment for Acute Cerebral Infarction
Experimental group:Standardized Western Medicine Treatment for Acute Cerebral Infarction+Tanhuo Pill
Sponsors
Xuanwu Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) First confirmed acute ischemic stroke; 2) Meets the diagnostic criteria for phlegm heat syndrome in traditional Chinese medicine; 3) The onset time of symptoms of acute ischemic stroke is within 72 hours; 4) MRS score = 2 points before the onset of stroke symptoms; 5) Failure to undergo intravenous or arterial thrombolysis and endovascular intervention therapy; 6) NIHSS score, 5 = score = 15; 7) Age range from 18 to 85 years old; 8) Sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Hemorrhagic cerebrovascular disease (confirmed by head MRI including subarachnoid hemorrhage cerebral hemorrhage and other intracranial hemorrhage); Cardiogenic cerebral embolism; Unidentified or other cause ischemic stroke; Brain tumors traumatic brain injury parasitic brain diseases etc; 2) Transient cerebral ischemia (TIA) and reversible ischemic neurological deficit (RIND); 3) Severe systemic diseases including but not limited to: 1) Cardiac dysfunction: myocardial infarction heart failure; 2) Liver dysfunction: Total bilirubin>3mg/dL albumin178 µ Mol/L (2mg/dL) urea nitrogen>18mmol/L (40mg/dL); 4) Digestive system diseases: peptic ulcers gastrointestinal bleeding etc.; 5) Malignant tumors; 4) Individuals who are allergic to the components of Tan Huo Wan; 5) Mental disorders that affect drug evaluation such as depression anxiety dementia epilepsy etc; 6) Women with recent family planning as well as pregnant and lactating women; 7) Subjects who are unable to understand informed consent or unwilling to provide personal information and do not wish to enter the study;
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| ADL;IL-6;National Institute of Health stroke scale;hs-CRP;mRS;Traditional Chinese Medicine Syndrome Score; | — |
Primary
| Measure | Time frame |
|---|---|
| Ratio of subjects with mRS scores of 0-1; | — |
Countries
China
Contacts
Public ContactWang ningqun
Xuanwu Hospital, Capital Medical University
Outcome results
None listed