Stable Coronary Heart Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for stable coronary heart disease and satisfy at least one of the following conditions with stable symptoms: 1) Coronary artery imaging or coronary angiography confirms that at least one coronary artery has a stenosis >50%; 2) History of previous myocardial infarction with a duration >3 months; Post coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) with a duration >3 months; (2) Age between 18 to 79 years old; (3) Classified as Canadian Cardiovascular Society (CCS) angina grades I to III; (4) Have not participated in rehabilitation training within the past month; (5) Signed the informed consent form and voluntarily participate in this study.
Exclusion criteria
Exclusion criteria: (1) Patients with other severe diseases that affect life expectancy (severe aortic stenosis, decompensated heart failure, acute pulmonary embolism, deep vein thrombosis, acute pericarditis or myocarditis, aortic dissection, left main stem stenosis, malignant tumors) or those with functional disabilities who cannot take care of themselves; (2) Uncontrolled hypertension or systolic blood pressure =160mmHg and/or diastolic blood pressure =100mmHg even with antihypertensive medication; (3) Uncontrolled arrhythmias that cause symptoms or hemodynamic disturbances; (4) Patients with absolute and relative contraindications for cardiopulmonary exercise testing; (5) Chronic lung disease with symptoms of dyspnea; (6) Recent stroke or transient ischemic attack, with cognitive dysfunction or psychiatric disorders; (7) Uncorrected clinical issues such as infections, severe anemia, electrolyte disturbances, hyperthyroidism, etc.; (8) Abnormal liver and kidney function (alanine aminotransferase or creatinine >2 times the upper limit of the normal reference range); (9) Individuals with a habit of regular exercise (fixed exercise time =30 minutes/day or 3 hours/week); (10) Those who have participated in other drug clinical trials or interventional studies within the last month; (11) Any other conditions deemed unsuitable for participation in the study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| peak vo2; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM;LVMI;peak BR;SF-36;LVEF;peak vo2/ HR;peak VE;MET;SAQ;AT;CCS;VE/VCO2; | — |
Countries
CHINA
Contacts
The Fourth Affiliated Hospital of Xinjiang Medical University