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The Construction and Clinical Application of a Surrogate Endpoint System for Traditional Chinese Medicine in the Treatment of Diabetic Kidney Disease

The Construction and Clinical Application of a Surrogate Endpoint System for Traditional Chinese Medicine in the Treatment of Diabetic Kidney Disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025000223
Enrollment
Unknown
Registered
2025-02-08
Start date
2025-02-13
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Kidney Disease

Interventions

non-Exposure group:Not taking Chinese medicine
Exposure group:Exposure factor: Use of traditional Chinese medicine

Sponsors

Dongzhimen Hospital Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Age 18 years or older diagnosed with stage IV diabetic kidney disease (DKD) according to the KDIGO guidelines and China's DKD Prevention and Treatment Guidelines; (2) Baseline eGFR > 15 ml/min/1.73m²; (3) Willing to participate in the observational study and able to cooperate with follow-up; (4) No gender restrictions.

Exclusion criteria

Exclusion criteria: (1) Other types of chronic kidney disease (such as primary or secondary glomerular diseases); (2) Kidney transplant recipients or patients who have undergone dialysis treatment; (3) Pregnant or breastfeeding women; (4) Comorbid severe cardiovascular or cerebrovascular diseases or other life-threatening systemic diseases.

Design outcomes

Primary

MeasureTime frame
Surrogate Endpoints;Doubled in Serum Creatinine;The glomerular filtration rate < 15ml/min/1.73?;

Secondary

MeasureTime frame
Urine microalbumin;Hospitalization for Acute Heart Failure;Acute Coronary Syndrome;Ischemic Stroke;All-Cause Mortality Rate;

Countries

China

Contacts

Public ContactCAO CAN

Dongzhimen Hospital Beijing University of Chinese Medicine

ashlycaocan@163.com15210946484

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026