Sepsis
Conditions
Interventions
Conventional treatment Group:Basic treatment of sepsis
Sijunzi decoction Group:Sijunzi decoction is fed orally or nasally
Sponsors
Yancheng TCM Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: (1) The Sepsis3.0 diagnostic criteria for sepsis jointly issued by the American Society of Critical Care Medicine and the European Society of Critical Care Medicine in 2016 were met and immunosuppression was present namely LYM < 1.0×109/L; (2) In 2013 Expert Consensus on Diagnosis and Treatment of Sepsis in Combination of traditional Chinese and Western Medicine and the dialectical treatment principle of "four syndroms and four methods" in combination of traditional Chinese and Western medicine proposed by Professor Wang Jida's team were deficiency syndrome.
Exclusion criteria
Exclusion criteria: (1) Patients who have used hormones immunosuppressants or other immune stimulants in the past 1 month; (2) Terminal stage of malignant tumor; (3) A history of liver lung kidney bone marrow transplantation; (4) Women during pregnancy; (5) There are patients who are contraindicated to take TCM decoction; (6) Patients and family members unanimously give up active rescue take the initiative to withdraw or lost visitors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lymphocyte count; | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of curative effect of TCM syndrome;NK;The maximum dose of vasoactive drugs applied;GCS;CD3+;IL-6;SOFA;IgG;Blood purification time;CRP;CD4+/CD8+;TCM syndrome integral;Fluid infusion in 24 hours;28-day survival;WBC;Vasoactive drug application time;IgM;PCT;Length of ICU stay;HLA-DR;APACHE?;Lac;90-day survival;Mechanical ventilation time; | — |
Countries
China
Contacts
Public ContactGongjie
Yancheng TCM Hospital
Outcome results
None listed