Atopic Dermatitis
Conditions
Interventions
Observation group:Glyceryl trillinoate cream
Control group:Basic emollient
Sponsors
The First Affiliated Hospital of Naval Military Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) in line with the diagnostic criteria of traditional Chinese and western medicine, a clear diagnosis of atopic dermatitis patients; (2) Age =2 years and =75 years; Gender is not limited; (3) The patient had a history of moderate and severe atopic dermatitis; (4) The patient was in remission of AD, and the IGA score of skin lesions was = 1 for 2 weeks; (5) All patients or guardians have signed informed consent forms, among which, patients aged 2-8 (< 8) have signed informed consent forms by guardians; For patients aged 8-18 (< 18), the informed consent form shall be jointly signed by the patient and the guardian; Patients aged 18-75 are informed consent signed by patients.
Exclusion criteria
Exclusion criteria: (1) Patients in acute stage with erosion, exudation and secondary infection; (2) allergic to the test article and its components; (3) Patients who are currently participating in other clinical studies or have participated in other clinical studies within one month; (4) Patients with other skin diseases except AD in the area to be treated; (5) Suffering from severe liver and kidney diseases, blood system diseases, autoimmune diseases, chronic severe infections, diabetes or mental diseases, and taking drugs or drinking alcohol; (6) Suffering from malignant tumor or other serious diseases that may affect the correct evaluation of curative effect; (7) Discontinued with duprizumab for =12 weeks, or stopped with JAK inhibitor for =1 week; (8) Patients who have systematically used hormones, other immunosuppressants or phototherapy; (9) Other reasons that the researcher thinks can't be selected (such as poor compliance and failure to follow up on schedule).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatology Life Quality Index;Investigator Global Assessment;Visual Analogue Scale;Eczema Area and Severity Index;IgE;Th1/Th2/Th17; | — |
Countries
China
Contacts
Public ContactYang Yanlong
The First Affiliated Hospital of Naval Military Medical University
Outcome results
None listed