Skip to content

Exploration of post stroke dysphagia neural rehabilitation mechanism treated by acupuncture based on the theories of TRPV1 activating and up-regulating autophagy and eNOS phosphorylation.

Exploration of post stroke dysphagia neural rehabilitation mechanism treated by acupuncture based on the theories of TRPV1 activating and up-regulating autophagy and eNOS phosphorylation.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000190
Enrollment
Unknown
Registered
2025-01-26
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post stroke dysphagia

Interventions

Treatment Group:Rehabilitation+acupuncture
Control Group 1:Rehabilitation+capsaicin
Control Group 2:Rehabilitation

Sponsors

Affiliated Hospital of Gansu University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) The clinical diagnosis is the first cerebral infarction or cerebral hemorrhage and confirmed by CT or MRI of the brain; (2) Definite dysphagia in the oral or pharyngeal phase; (3) The duration of stroke and dysphagia is between 1 and 6 months; (4) The patient was conscious his vital signs were stable and there was no fever and lung infection; (5) Age 50-75 years; (6) Informed consent

Exclusion criteria

Exclusion criteria: (1) Patients with tumors severe heart lung liver and kidney dysfunction; (2) Those who suffer from Parkinson's disease encephalitis and other neurological diseases at the same time; (3) Combined with severe cognitive dysfunction and aphasia; (4) Those who are unable to complete the skull MRI examination and cannot cooperate with the examination and treatment; (5) Craniotomy patients.

Design outcomes

Primary

MeasureTime frame
SP\CGRP\TNF-?\IL-1\IL2 levels in saliva;

Secondary

MeasureTime frame
mean velocity and pulsatility index of Middle cerebral artery and Basilar artery;videofluoroscopic swallowing study score;

Countries

China

Contacts

Public ContactLiya Mao

Affiliated Hospital of Gansu University of Chinese Medicine

113210965@qq.com13679478370

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026