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Study on the effects of acupuncture on nutritional status and intestinal mucosal barrier mechanism in patients with severe stroke

Study on the effects of acupuncture on nutritional status and intestinal mucosal barrier mechanism in patients with severe stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000177
Enrollment
Unknown
Registered
2025-01-25
Start date
2021-06-02
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe stroke

Interventions

Regular Group:Receive early enteral nutrition suspension treatment and conventional medication treatment within 48 hours of admission
Observers:Receive early enteral nutrition suspension treatment and conventional medication treatment within 48 hours, in addition to acupuncture

Sponsors

Affiliated Hospital of Hebei University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Meets the above diagnostic criteria and the onset time is within 72 hours; (2) Individuals with a history of stroke but no significant residual neurological deficits; (3) AGI meets grades I-II; (4) Age range of 20-80 years old; (5) Hospitalization time = 7 days; The patient or family member is informed and signs an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with contraindications to enteral nutrition such as gastrointestinal perforation intestinal obstruction postoperative gastrointestinal surgery and intestinal fistula; (2) Patients with intestinal tumors; Pregnant or lactating women; (3) Individuals with skin infections ulcers or scars who are not suitable for acupuncture treatment; (4) The condition is endangered and the estimated survival time is less than 7 days; (5) Patients with deteriorating hemodynamic status requiring an increase in the dosage of vasoactive drugs; (6) Patients undergoing emergency surgery traumatic brain injury and thrombolytic therapy; (7) Family members refused to enter this researcher.

Design outcomes

Primary

MeasureTime frame
DAO;D-LA;

Secondary

MeasureTime frame
HGB;IL-8;BAX;PA;Bax mRNA;Ig-A;ALB;ZO-1;Occludin;IL-6;Bcl-2 mRNA;Bcl-2;

Countries

China

Contacts

Public ContactQin Liang

Affiliated Hospital of Hebei University

2522032704@qq.com15030228082

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026