Sepsis-induced Myopathy
Conditions
Interventions
Experimental group:Basic treatment of Sepsis and Qiang-Ji-Jian-Li Formula
Control group:Basic treatment of Sepsis
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Participants must be aged between 18 and 85 years. 2. Participants must satisfy the diagnostic criteria for Sepsis 3.0. 3. Participants must fulfill the diagnostic criteria for Sepsis-induced Myopathy. 4. The patient or an immediate family member or legal representative must provide agreement and sign a written informed consent document.
Exclusion criteria
Exclusion criteria: 1. A confirmed pregnancy or the urine ß-HCG test is positive. 2. Newly identified primary neuromuscular disease upon admission. 3. Individuals who are unable to complete Rectus Femoris Cross-sectional Area measurements due to leg amputation pelvic or femoral fractures or knee or hip arthroplasty. 4. Patients diagnosed with Metastatic tumors (PD) or currently undergoing chemotherapy. 5. Patients who have received long-term treatment with oral corticosteroids. 6. Individuals who were unable to walk independently or with assistive devices prior to the onset of sepsis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality in 28-day;All-cause mortality in 1-year;Rectus Femoris Cross-sectional Area; | — |
Secondary
| Measure | Time frame |
|---|---|
| Unplanned ICU readmission;Oxygen uptake rate;Pv-aCO2;Duration of prone ventilation;Duration of invasive/non-invasive mechanical ventilation;Unplanned hospital readmissions;Oxygen consumption index;Medical Research Council-Sum Score;Oxygen delivery index;Infection-related results;Duration of hospitalization in days;lactic acid; Duration of stay in the ICU; | — |
Countries
China
Contacts
Public ContactWei-Tao Chen
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed