generalized anxiety disorder
Conditions
Interventions
Control group:Treatment as usual(TAU) + sham acupuncture(shallow needling next to the acupoint, electricity off)
Intervention group:Treatment as usual(TAU) + electroacupuncture(Acupoints: Baihui, Shenting, Neiguan, Hegu, Taichong, Sanyinjiao, Guanyuan, and Zusanli. Parameter: continuous wave, 100Hz, intensity ba
Sponsors
The second Xiangya hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Subjects were determined to meet the diagnostic criteria for Generalized Anxiety Disorder (GAD) as per the DSM-5 through the Structured Clinical Interview for DSM Disorders (SCID) with a Hamilton Anxiety Rating Scale (HAMA) score greater than 14 points 2. Age range: 18-60 years old; 3. Participants had not received any pharmacological treatment for at least 4 weeks prior to the trial commencement or had been on stable pharmacological treatment for over 4 weeks. 4. Participants should have an educational level of junior high school or above and possess the capability to sign an informed consent form as well as to complete self-rating scales and cognitive assessments. 5. Participants are required to sign an informed consent document.
Exclusion criteria
Exclusion criteria: 1.Diagnosed as organic mental disorders or other mental disorders in DSM-5 except for anxiety disorders. 2.Individuals with severe suicidal ideation or a history of suicide attempts. 3.Individuals who have used beta-blockers within the past month; those with irregular caffeine intake should discontinue caffeine and those who consume caffeine daily should reduce their intake by half. 4. individuals who have received other non-pharmacological treatments within the last six months such as acupuncture Electroconvulsive Therapy (ECT) Repetitive Transcranial Magnetic Stimulation (rTMS) or systematic psychotherapy for a total of more than 10 sessions 5.Individuals with a history of alcohol and substance dependence. 6.Individuals with a history of cranial trauma or coma. 7.Individuals with brain organic lesions severe somatic or chronic somatic diseases that are not well controlled (such as thyroid diseases hemophilia lupus erythematosus or rheumatoid arthritis and other immune system diseases lung liver kidney damag
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMA score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Questionnaire on Living and Dietary Habits;SCOPA-AUT score;PHQ-15 score;HAMD score;BSI score;TESS score;Height;Face image;GAD-7 score;11-item heart rate and respairation scale;Demographic data;Single-cell sequencing;Flow cytometry;PHQ-9 score;STAI score;Pulse condition;TCM syndrome differentiation;Weight;Medication Dosage Log;Tongue image;Autonomic nervous function;cognitive assessments; | — |
Countries
China
Contacts
Public ContactJin Liu
The second Xiangya hospital of Central South University
Outcome results
None listed