Diabetic kidney disease
Conditions
Interventions
TS_QK group:Basic treatment ( Take Dapagliflozin as the basic blood sugar control plan)+TangShenFang granule of all-square mixed extraction
TS_K1 group:Basic treatment ( Take Dapagliflozin as the basic blood sugar control plan)+Tangshenfang dispensing granule
control group:Basic treatment ( Take Dapagliflozin as the basic blood sugar control plan)+placebo
TS_K2 group:Basic treatment ( Take Dapagliflozin as the basic blood sugar control plan)+Tangshenfang dispensing granule 0.7 times dosage
Sponsors
GuangDong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1: Meet the diagnostic criteria of type 2 diabetes and diabetic kidney disease of stage ?? 2: Fasting blood glucose less than 8mmol/L and 2-hour postprandial blood glucose less than 11mmol/L 3: Older than 18 and younger than 75 4: Participate in the study voluntarily and sign the informed consent form
Exclusion criteria
Exclusion criteria: 1: Women who are pregnant preparing for pregnancy or nursing 2: Patients with acute complications of diabetes mellitus 3: Complicated with serious liver and kidney function damage or serious primary diseases of respiratory circulatory digestive urinary and blood systems. 4: People with allergies and previous allergies to the drugs of this study 5: People with proteinuria caused by other reasons 6: Patients participating in clinical trials of other drugs 7: People with mental illness or disobeying the doctor's advice and be failure to cooperate with treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine albumin creatinine ratio;Serum creatinine;Estimated glomerular filtration rate;Blood urea nitrogen;Urine protein creatinine ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Triglyceride;2-hour postprandial blood glucose;Total cholesterol;Low-Density Lipoprotein Cholesterol;High density lipoprotein cholesterol;Glycated hemoglobin;Traditional Chinese medicine syndrome score;Fasting blood glucose; | — |
Countries
China
Contacts
Public ContactZhao Ling
GuangDong Provincial Hospital of Chinese Medicine
Outcome results
None listed