Chronic heart failure
Conditions
Interventions
Experimental group Group:In the experimental group, on the basis of the conventional treatment of Western medicine, the addition of Sheng Maijiuxintang
Control Group:According to the 2018 Chinese Guidelines for the Diagnosis and Treatment of Heart Failure, conventional Western treatment involves blood pressure control in hypertensive patients, blood
Sponsors
Wuxi Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine China
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: (1) aged 18 years or older gender is not limited; (2) meet the diagnostic criteria of ADHF; (3) meet the Chinese medicine diagnostic criteria of heart failure disease with qi and yin deficiency and yang deficiency and blood stasis; (4) NYHA cardiac function class III-IV; (5) LVEF = 49%; (6) have informed understanding of the study and sign the informed consent for the trial; and (7) have good adherence to the follow up. Translated with www.DeepL.com/Translator (free version)
Exclusion criteria
Exclusion criteria: (1) myocardial infarction or unstable angina within 1 month; (2) severe hepatic and renal insufficiency (glomerular filtration rate (eGFR) 120 U/L); (3) systolic blood pressure <80 mmHg with hypoperfusion or cardiogenic shock; (4) women in preparation for pregnancy during pregnancy or during breastfeeding; (5) suffering from other serious diseases malignant tumor severe hyperthyroidism severe infection severe anemia high degree of atrioventricular block severe valvular disease of the heart etc.; (6) patients with clear contraindications to the experimental underlying Western therapeutic drugs; (7) patients who participated in other clinical trials during the observation period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Human hypoxia-inducible factor 1 alpha;N-terminal brain natriuretic peptide precursor;Human cystatinase 3;Human vascular endothelial growth factor A;left ventricular ejection fraction;Heart Function Classification (NYHA Classification); | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese medicine evidence points;Comparison of the number of heart failure hospitalizations at 1 month post-discharge;Chinese medicine evidence efficacy;6-minute walking distance; | — |
Countries
China
Contacts
Public Contactzhao yang
Wuxi Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine China
Outcome results
None listed