Postoperative cognitive dysfunction
Conditions
Interventions
Sham acupuncture group:sham acupuncture
Electroacupuncture group:Electroacupuncture
Sponsors
Shuguang hospital affiliated to Shanghai University of Traditional Chinese Medicin
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age 65~80 years old; (2) Primary school education level or above; (3) Informed consent voluntarily participate in this trial; (4) ASA is graded I-II.
Exclusion criteria
Exclusion criteria: (1) Patients with severe central nervous system diseases and severe mental illnesses before surgery; (2) Patients undergoing brain surgery; (3) The preoperative Mini-mental State Examination (MMSE) examination was less than 24 points; (4) Patients with drug abuse alcoholism and preoperative depression tendency; (5) Slow arrhythmia resting heart rate of < 60 beats/min for any reason; (6) severe hearing and vision impairment; (7) Patients with skin scars incisions and infections at the meridian acupoints; (8) Emergency trauma patients; (9) Patients who do not agree to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the neurocognitive assessment scale of the patient after 7 days and 1 month after surgery.; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Confusion Assessment Method;Time from cessation of all anesthetic infusions to patient's request to open eyes, tracheal extubation time, and return of consciousness.;Comparison of sleep quality assessment before and after surgery.;Changes in inflammatory factors IL-1ß, IL-6, TNF-a before and 5 days after surgery;Postoperative pain level;S-100ß protein;Plasma neurotransmitters and plasma protein profiles;the differences in length of hospital stay and postoperative complications among patients;Differences in postoperative depression and anxiety levels among patients; | — |
Countries
China
Contacts
Public ContactCHOI HUA SHUN
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed