HFpEF
Conditions
Interventions
Treatment group:GDMT+5% Glucose solution 250ml+Yiqi Fumai (freeze-drying) injection 8 pieces
control group:GDMT+5% Glucose solution250ml
Sponsors
Jiangsu Province Hospital on Integration of Traditional Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Meet the Western diagnostic criteria for HFpEF; (2) The cause of heart failure is ischemic heart disease; (3) Consistent with the main syndrome of qi and yin deficiency in traditional Chinese medicine; (4) Cardiac function is classified as NYHA functional class II-III; (5) Age range: 18-75 years old; (6) Stable clinical conditions during enrollment and randomization; (7) Enjoy the right to know and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Acute coronary syndrome; (2) Active myocarditis or pericarditis; (3) Patients with severe heart failure and heart function grade IV; (4) Atrial fibrillation and diabetes were associated; (5) Planned extracardiac surgery; (6) Combined with serious diseases such as liver kidney malignant tumors endocrine system and hematopoietic system; (7) Individuals with mental disorders and unwillingness to cooperate; (8) Pregnant or lactating women; (9) Any factors that can increase mortality such as cardiogenic shock severe ventricular arrhythmia pericardial tamponade pulmonary embolism and severe infections.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| dp/dv;Six Minute Walk Distance;E/e';Traditional Chinese Medicine Syndrome Points;Serological indicators(sST2\NT-ProBNP\hs-CRP\IL-6\IL-11\Piezo1);Clinical efficacy evaluation of traditional Chinese medicine;E/A; | — |
Primary
| Measure | Time frame |
|---|---|
| ?GLS; | — |
Countries
China
Contacts
Public ContactLixing Wu
Jiangsu Province Hospital on Integration of Traditional Chinese and Western Medicine
Outcome results
None listed