Delirium after deep brain electrode implantation in patients with Parkinson's disease
Conditions
Interventions
control group:In the anesthesia preparation room, the acupuncturist in charge sanitize the buccal acupoints (both sides of the head points, upper jiao point, middle jiao point, and lower jiao point) w
intervention group:The acupuncturist in charge performs acupuncture at the buccal acupoints (both sides of the head points, upper jiao point, middle jiao point, and lower jiao point) using disposable
Sponsors
Tsinghua University Yuquan Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed with Parkinson's disease and proposed to undergo deep brain stimulation implantation; (2) American Society of Anesthesiologists (ASA) grade I to III; (3) Informed consent voluntary subjects the process of obtaining informed consent conforms to the provisions of GCP.
Exclusion criteria
Exclusion criteria: 1)A history of neurological or mental illness; 2)Severe audio-visual impairment language impairment and/or communication difficulties resulting in inability to communicate; 3) Alcohol dependence and drug addiction; 4) Abnormal coagulation function puncture site infection. 5) A diagnosis of dementia is made based on the MMSE score: illiterate = 17 points primary school education = 20 points secondary school education (including technical secondary school) = 22 points and college education (including junior college) = 23 points.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of postoperative delirium (POD) within 7 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cerebral oxygen monitoring;Serological markers (IL-1ß, TNF-a, IL-6, and S100ß).;Severity and duration of delirium;Anesthesia stability: Blood pressure, heart rate, depth of anesthesia index BIS (Bispectral Index),body temperature; | — |
Countries
China
Contacts
Public ContactFan Ting
Tsinghua University Yuquan Hospital
Outcome results
None listed