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Randomized double-blind controlled multicenter clinical trial of Wendan Decoction granules in the treatment of non-alcoholic fatty liver disease with phlegm turbid internal resistance

Randomized double-blind controlled multicenter clinical trial of Wendan Decoction granules in the treatment of non-alcoholic fatty liver disease with phlegm turbid internal resistance

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000136
Enrollment
Unknown
Registered
2025-01-16
Start date
2025-01-20
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nafld

Interventions

Test group 1:Wendan Decoction standard dose granules+conventional treatment
Test group 2:Wendan Decoction reduced dose granules+conventional treatment
control group:Placebo granules+conventional treatment

Sponsors

Jiangyin Hospital of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. patients who meet the diagnostic criteria of NAFLD; 2. patients with phlegm turbid internal resistance syndrome differentiation in traditional Chinese medicine; 3. patients aged 18-70 years old; 4. patients who signed informed consent and had high compliance.

Exclusion criteria

Exclusion criteria: 1. patients with severe primary diseases such as heart liver kidney lung brain endocrine and hematopoietic system in the past or at the time of enrollment; 2. patients with acute coronary syndrome malignant arrhythmia and other serious heart diseases confirmed by examination; 3. patients with infection malignant tumor or mental illness; 4. patients with allergic constitution or allergic to the drug; 5. pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Total effective rate;

Secondary

MeasureTime frame
HbA1c;ALT;TC;TG;HDL-C;FBG;

Countries

China

Contacts

Public ContactHuahaibing

Jiangyin Hospital of traditional Chinese Medicine

jyzy3288@163.com17768318099

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026