Parkinson's Disease(PD)
Conditions
Interventions
Treatment group:Conventional anti-Parkinson drugs were used+Take Schisandrin recipe
Control group:Conventional anti-Parkinson drugs were used
Sponsors
Wenzhou Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: The general inclusion criteria were: 1. 20-80 years old; 2. taking stable medications within the past month; PD patients were included in the study if they also met the following criteria: 1. both met the above diagnostic criteria of traditional Chinese and western medicine; 2. According to TCM syndrome differentiation it belongs to the sea of marrow deficiency type; 3. Evaluation of patients with revised Hoehn-Yahr stage 1-3; 4. Dopamine replacement and other drugs were taken stably for more than 1 month; 5. voluntarily participated in the study and signed the informed consent; 6. those with correct understanding of the significance of this study and good compliance.
Exclusion criteria
Exclusion criteria: 1. Parkinsonism or Parkinsonism plus syndrome caused by drugs toxins infections cerebrovascular diseases and metabolic diseases; 2. complicated with other major diseases such as liver and kidney blood immune system; 3. Participating in other drug clinical trials at the same time; 4. those with severe mental illness who are unable to cooperate; 5. Unable to cooperate with fNIRS examination or have contraindications to fNIRS examination; 6. other patients who did not meet the diagnostic and inclusion criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Unified Parkinson's Disease Rating Scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Webster symptom Scale score;Changes in blood oxygen in the prefrontal lobe of the brain;Score of TCM syndrome integral scale;Parkinson's Cognitive function Rating Scale score;Montreal Cognitive Assessment scale score; | — |
Countries
China
Contacts
Public ContactZhi Yinghao
Wenzhou Hospital of Traditional Chinese Medicine
Outcome results
None listed