Acute pharyngitis in children
Conditions
Interventions
control:Standard treatment using western medicine. The course of treatment was 5 days. 1) Antipyretics and analgesics: ibuprofen suspension or acetamiphen as needed. 2) Antibacterial drugs: amoxicilli
experimental:Standard Western medical treatment was used in combination with ErTong QingYan JieRe KouFuYe. The course of treatment was 5 days.Usage and dosage follow the instructions.
Sponsors
Zhoukou Central Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1) the child's legal guardian gave informed consent and signed an informed consent form; 2) meeting the Western medical diagnostic criteria for acute pharyngitis in children; 3) Comply with the TCM diagnostic criteria of syndrome/pattern of heat invading lung and stomach; 4) Age 1 to 14 years old gender is not limited; 5) Duration of illness = 48 hours; 6) WBS sore throat score =4; 7) Children with McIsaac score =2 (viral infection) or McIsaac score =3 (bacterial infection);
Exclusion criteria
Exclusion criteria: 1) Local complications such as retropharyngeal abscess parapharyngeal abscess and peritonsillar abscess acute otitis media acute rhinosinusitis acute laryngotracheitis acute bronchitis and even pneumonia. Rheumatic fever acute glomerulonephritis acute arthritis rheumatic fever cardiac complications etc; 2) Children with scarlet fever and serous disease; 3) children with combined measles infectious mononucleosis; 4) children with severe primary diseases of the heart liver kidney and hematopoietic system diabetes mellitus and mental illness; 5) Children who are allergic or hypersensitive to test drugs (allergic to 2 or more foods or drugs); 6) children with the following abnormal laboratory indicators: 1) abnormal renal function (blood creatinine SCr is greater than the upper limit of normal values); 2) glutamic oxal transaminase (AST) alanine aminotransferase (ALT) exceeds the upper limit of the normal value of more than 50% (1.5 times); 3) clinically significant cardiac arrhythmia; 7) Children with malignant tumors; 8) Children who have participated in other clinical observations within the last 1 month; 9) Children who in the opinion of the investigator are not suitable for clinical observation. Children who meet any of the above criteria should be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to onset of sore throat relief (WBS); | — |
Secondary
| Measure | Time frame |
|---|---|
| number of days of antibiotic use;efficacy of TCM syndrome manifestation.;Analysis of decline in single symptom scoring;Number of antipyretic and analgesic administrations.;total leukocyte count, neutrophil percentage, and C-reactive protein level.; | — |
Countries
the People's Republic of China
Contacts
Public ContactZhenlin Ma
Zhoukou Central Hospital
Outcome results
None listed