post-stroke aphasia
Conditions
Interventions
Experimental group:"Yisui Xingshen" acupuncture+Basic medical therapy+Language rehabilitation training
Control group:Non-channel non-point fake acupuncture+Basic medical therapy+Language rehabilitation training
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 80 Years
Inclusion criteria
Inclusion criteria: A The diagnosis meets the ischemic stroke disease criteria in the Chinese guidelines for diagnosis and treatment of acute ischemic stroke 2018 and the onset time of the patient is within 14-30 days (including 14 and 30 days); B Motor Aphasia was diagnosed by the Western Aphasia Battery (WAB); C The severity of the patient's Aphasia was assessed by the Boston Diagnostic Aphasia Examination (BDAE) at 2-4 grades which could be assessed with the linguistic scale; D Right-handed (left-brain advantage) native speaker of Chinese patients regardless of gender between 35 and 80 years old (including 35 and 80 years old) with primary school education or above; E The condition was stable with unconsciousness disorder and no other non-vascular cognitive dysfunction; F There is no metal in the body and no contraindications for MRI and the patient can cooperate to complete the 20-minute MRI.
Exclusion criteria
Exclusion criteria: A Patients with severe non-verbal cognitive auditory visual or phonological dysfunction resulting in inability to cooperate with the scale evaluation; B Language dysfunction due to congenital or childhood disease; C Being pregnant or lactating; D With bleeding tendencies; E Patients with serious abnormalities of heart liver kidney and other important organs are deemed unfit to participate in this study after evaluation; F Patients with implanted pacemakers or those with severe arrhythmias or local skin infections.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Aphasia Quotient after 4 weeks of intervention ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in MMSE score after 4 weeks of intervention and 90 days after enrollment;Changes in Aphasia Quotient after 90 days of enrollment;Changes in daily living ability score after 4 weeks of intervention and 90 days after enrollment;Changes in NIHSS score after 4 weeks of intervention and 90 days after enrollment;Changes of structural brain network and brain age difference after 4 weeks of intervention;Changes in MoCA score after 4 weeks of intervention and 90 days after enrollment; | — |
Countries
China
Contacts
Public ContactJiaqin Huang
Beijing Hospital
Outcome results
None listed