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Clinical efficacy and safety study of Zhichuanling oral solution in the treatment of cough variant asthma

Clinical efficacy and safety study of Zhichuanling oral solution in the treatment of cough variant asthma

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000102
Enrollment
Unknown
Registered
2025-01-14
Start date
2024-12-23
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough variant asthma

Interventions

Test group:Oral Zhichuanling oral liquid10ml once three times a day
Control group:Salmeterol fluticasone powder inhaler 50ug/100ug each time twice a day. At the same time oral Zhichuanling oral liquid placebo was given 10ml once three times a day.

Sponsors

Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1)According to the CVA diagnostic criteria 2)The first diagnosis was CVA and the cough symptom score was = 6 3)Age 18-65 4)Sign informed consent and be willing to accept corresponding treatment and follow-up

Exclusion criteria

Exclusion criteria: 1)Those who had previously diagnosed CVA and received systematic treatment or who received systematic anti asthma drug treatment or traditional Chinese medicine treatment for cough and asthma within 4 weeks before the study were included 2)Patients with severe primary diseases such as circulatory system respiratory system digestive system urinary system endocrine system and hematopoietic system patients with tumors and patients with severe infection water electrolyte and acid-base balance disorders. 3)Patients allergic to the drugs used in this study 4)Those who are participating in other drug clinical trials or have participated in other clinical trials within 3 months 5)Patients forbidden or cautious in the manual of Zhichuanling oral liquid: Patients with glaucoma pregnant women patients with severe hypertension coronary heart disease prostate hypertrophy urinary retention and athletes 6)People who are forbidden or cautious in the instructions of salmeterol fluticasone inhalation: those who have a history of allergy to any component or excipient in this product such as excipient milk protein and those who are allergic to milk;

Design outcomes

Primary

MeasureTime frame
Daytime cough clinical symptom score;

Secondary

MeasureTime frame
Recurrence rate of symptoms after drug withdrawal;Daytime cough symptom score after withdrawal;Quality of life score;Daytime cough clinical symptom score;Changes in airway responsiveness;Changes of immunological indicators;

Countries

China

Contacts

Public ContactXixiaotu

Guangdong Provincial Hospital of Chinese Medicine

xixiaotu@163.com13929556092

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026