MAFLD
Conditions
Interventions
ganzhixiao group:ganzhixiao capsule
Sponsors
Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Age between 18 and 70 years old with a body mass index (BMI) of at least 24kg/m2; 2) Diagnosis of NAFLD determined by imaging [ultrasound computed tomography or magnetic resonance imaging (MRI-PDFF)] or liver biopsy showing MAFLD or simple steatosis within the last 24 months prior to screening; 3) MAFLD patients conform to the damp heat syndrome type; 4) Voluntary signing of informed consent form
Exclusion criteria
Exclusion criteria: 1) Blood biochemical indicators ALT AST BUN are greater than 1.5 times the upper limit of normal values Cr is greater than the upper limit of normal values eGFR<60ml/min/1.73m2; 2) Alcoholic fatty liver other chronic liver diseases cirrhosis liver malignant tumors etc.; 3) Type 2 diabetes and pancreatic diseases; 4)Taking some hypoglycemic lipid-lowering liver protective drugs or high-dose vitamin E that may affect the efficacy judgment in the past three months ; 5) Patients with severe infections cardiovascular respiratory renal hematological rheumatic connective tissue disease neuropsychiatric and non liver malignant tumors; 6) Pregnant or lactating women; 7) Those who require long-term hormone therapy; 8) Researchers anticipate poor compliance or inability to cooperate; 9) There are contraindications for MRI examination including pacemakers or cochlear implants postoperative artificia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver fat content; | — |
Secondary
| Measure | Time frame |
|---|---|
| ALT;body weight;CK18;PSQI;Waist hip height ratio;BMI;FIB-4;waist to hip ratio;hip circumference;LSM;Damp Heat Traditional Chinese Medicine Syndrome Scale;waist circumference;Zung Depression Self Rating Scale;Zung Self Rating Anxiety Scale; | — |
Countries
China
Contacts
Public ContactHui Dong
Tongji Hospital Affiliated to Tongji Medical College Huazhong University of Science and Technology
Outcome results
None listed