sepsis-induced liver injury
Conditions
Interventions
Treatment group:Treatment group was given standard dose of Dachaihu decoction for adults
Sponsors
Foshan Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 120 Years
Inclusion criteria
Inclusion criteria: (i) Meet the diagnostic criteria of sepsis; (ii) Meet the diagnosis of liver injury; (iii) Meet the diagnostic criteria of Chinese medicine; (iv) Age =18 and =85; (v) Those who voluntarily or their family members agreed to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with abnormal liver function not caused by sepsis; 2) Patients with underlying liver diseases including viral hepatitis liver abscess autoimmune liver disease cirrhosis hepatocellular carcinoma; 3) Patients with previous history of allergic reaction to traditional Chinese medicines; 4) Patients who do not have the conditions for enteral feeding; 5) Patients during pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| alkaline phosphatase, ALP;Aspartate transaminase, AST;Albumin, ALB;Total bilirubin, TBil;Alanine transaminase, ALT;?-glutamyl transpeptidase, ?-GT; | — |
Secondary
| Measure | Time frame |
|---|---|
| D- Dimer;Duration of mechanical ventilation;NEU%;Activated partial thromboplastin time, APTT;Creatinine, Cr;C--reactive protein, CRP;28-day survival status;Indicators of the efficacy of Chinese medicine signs and symptoms;Platelet, PLT;Blood urea nitrogen, BUN;neutrophilicgranulocyte, NEU;SOFA score;Length of ICU stay;Fibrinogen, FIB;White blood cell, WBC;Indicators of the efficacy of Chinese medicine signs and symptoms;APACHE II score;UMA;Procalcitonin, PCT;Prothrombin Time, PT; | — |
Countries
China
Contacts
Public ContactHe Mingfeng
Foshan Hospital of Traditional Chinese Medicine
Outcome results
None listed