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Mechanism of the Therapeutic Effects of Qingre Liangxue Formula on Psoriasis Vulgaris: a multi-Omics Analysis

Mechanism of the Therapeutic Effects of Qingre Liangxue Formula on Psoriasis Vulgaris: a multi-Omics Analysis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000088
Enrollment
Unknown
Registered
2025-01-13
Start date
2023-08-16
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psoriasis

Interventions

psoriasis:Oral decoction of Qinghe Liangxue Fang

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Adult patients (18-65 years) with plaque psoriasis meeting both Western and traditional Chinese diagnostic criteria; (2) Newly diagnosed treatment-naïve individuals; (3) No systemic treatments administered within the last 4 weeks; (4) Provided signed informed consent.

Exclusion criteria

Exclusion criteria: (1) Individuals experiencing stress-related conditions such as infection pregnancy childbirth or trauma; (2) Those with an allergic disposition or allergies to the components of the formula; (3) Patients with pustular arthropathic or erythrodermic psoriasis or concurrent autoimmune diseases; (4) Patients with severe primary illnesses uncontrolled by standard treatments.

Design outcomes

Primary

MeasureTime frame
proteomics;transcriptomics;metabolomics;

Secondary

MeasureTime frame
Measure Yourself Medical Outcome Profile;Visual analogue scale;Enzyme-LinkedImmunosorbnent Assay;Self-rating depression scale;Corneometer CM825;reversetranscription-PCR;Psoriasis area and severity index;High-frequency ultrasound of the skin;Hamilton Anxiety Scale;Physician's Global Assessment;Body Surface Area;Dermatology Life Quality Index;

Countries

China

Contacts

Public ContactYanping Bai

China-Japan Friendship Hospital

zhi@tsinghua.edu.cn13910758509

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026