acute bronchitis (including acute exacerbation of chronic bronchitis)
Conditions
Interventions
Control group:Guaifenesin and dextromethorphan hydrobromide capsules oral administration
Experimental group:Qiguanyan Pill oral administration
Sponsors
Beijing University of Chinese Medicine Third Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Compatible with the diagnosis of acute bronchitis or acute exacerbation of chronic bronchitis; (2) Compatible with the TCM diagnosis of phlegm-dampness accumulated in the lung; (3) Age 18-75 years old (including 18 years old and 75 years old) gender is not limited; (4) Voluntarily participate in this clinical trial give informed consent and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1)Patient with other diseases that present with symptoms like cough and sputum such as tuberculosis pneumonia bronchial asthma interstitial lung disease lung malignancy gastroesophageal reflux disease etc.; (2) Taking antibiotics cough and phlegm medicines and other herbal and chemical medicines that have an impact on the study within 1 week; (3) Renal function Cr greater than the upper limit of the reference value or liver function ALT AST > 1.5 times the upper limit of the reference value; (4) Patients with severe primary diseases such as heart brain liver kidney respiratory mental and hematologic diseases for example severe hypertension insomnia etc.; (5) Pregnant or lactating women or women who are planning to give birth within the last 3 months; (6) Allergy to two or more drugs or foods or allergy to the test drug (including positive drugs) or its components or excipients; (7) Mental retardation or psychiatric disorder; (8) Participation in other clinical trials within one month; (9) Patients who in the opinion of the investigator are not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cough Evaluation Test;Sputum symptom composite score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinalysis;TCM syndrome healing effects;Cough disappearance time/virtually disappearance time;Bronchitis Severity Score;Between-group differences in antibiotic use;Wheezing Symptom Score; | — |
Countries
China
Contacts
Public ContactWang Chengxiang
Beijing University of Chinese Medicine Third Affiliated Hospital
Outcome results
None listed