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A clinical study was conducted to investigate the potential of diffusion tensor imaging (DTI) in the diagnosis and efficacy evaluation of perianal abscesses with hyperthermic toxicity.

A clinical study was conducted to investigate the potential of diffusion tensor imaging (DTI) in the diagnosis and efficacy evaluation of perianal abscesses with hyperthermic toxicity.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000068
Enrollment
Unknown
Registered
2025-01-10
Start date
2024-04-01
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perianal abscess

Interventions

MR Group:Use of conventional MRI images
DTI group:Diffusion tensor imaging (DTI) sequences selected

Sponsors

Shanghai municipal Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria are as follows: 1. Informed consent and signed informed consent form. 2. Meeting the diagnostic criteria of perianal abscess according to both Western medicine and traditional Chinese medicine syndrome of heat and toxin. 3. Aged 18–80 years. 4. Willing to participate and cooperate in completing the required surgical treatment. 5. Agree to participate in this experimental study without accepting any other treatment options.

Exclusion criteria

Exclusion criteria: 1. Patients younger than 15 years old or older than 80 years old. 2. Patients who refuse to participate in the study. 3. Patients with severe primary diseases of the liver kidney hematopoietic system endocrine system cardiovascular and cerebrovascular system nervous system tuberculosis vertebral malformation malignant tumors or mental illness. 4. Patients with a suspected history of abuse of sedative-hypnotics opioid analgesics or alcohol. Patients with skin diseases or infectious diseases. 5. Individuals with metal implants who cannot undergo MRI. 6. Pregnant women women preparing to become pregnant or lactating women. 7. Individuals who are not suitable or unable to use this treatment for other reasons. 8. Individuals with mental disorders language disorders motor dysfunction or psychological diseases.

Design outcomes

Primary

MeasureTime frame
Recurrence rate at 6 months after surgery.;

Secondary

MeasureTime frame
The relationship between the abscess and the anal sphincter;The differences in the thickness of the various layers of the anal canal;rectum and the thickness of the anal sphincter and the internal and external sphincters of the patients.;Whether the anal sphincter was involved and whether the upper part of the anal sphincter is diseased;Location of the perianal abscess and Depth of the abscess in relation to the anal sphincter;The Wexner Anal Incontinence Score (Wexner 1990) is a tool used to assess the severity of anal incontinence.;Extent of involvement of the anal sphincter in the infection;The postoperative pain score (VAS);Peripheral blood samples were collected to determine levels of IL-1 IL-6 TNF-a and other inflammatory factors;

Countries

China

Contacts

Public ContactYan Chen

Shanghai municipal Hospital of Traditional Chinese Medicine

498357632@qq.com+86 159 2103 8033

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026