Cerebral small vessel disease
Conditions
Interventions
1:Oral butylphthalein soft capsules
2:Jiedu Yizhi prescription of Chinese medicine treatment+Oral butylphthalein soft capsules
Sponsors
The Third Affiliated Clinical Hospital of Changchun University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria (1) Patients who met the diagnostic criteria of cognitive impairment of cerebral small vessel disease of western medicine and traditional Chinese medicine MMSE score =26 points. (2) The presence of acute CSVD clinical symptoms including TIA lacunar syndrome or subclinical symptoms and the presence of anatomically relevant responsible lesions on MR DWI showed that the lesion was less than 20mm in the acute phase T1T2 or FLAIR showed that the lesion was 3-15mm in the non-acute phase; Or no clinical symptoms of acute CSVD imaging examination with two or more common imaging features of CSVD: lacunar infarction (number =1) leukoaraiosis (Fazekas grade =2) or other combination of fused lesions including microbleeds (number >1 in depth) enlarged perivascular space (number =10 in basal ganglia); (3) patients in stable condition without other serious clinical complications. (4) the course of disease was within 12 months; (5) those who cooperate with the examination and are willing to be evaluated. (6) can accept traditional Chinese medicine treatment not allergic to traditional Chinese medicine. (7) patients over 60 years old. (8) voluntarily participate in this experimental study.
Exclusion criteria
Exclusion criteria: Exclusion Criteria (1) complicated with important organ dysfunction or other serious physical diseases. (2) patients under 60 years old; (3) those who could not cooperate with the evaluation. (4) those who are allergic to traditional Chinese medicine and do not accept traditional Chinese medicine treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA);Mini-mental State Examination (MMSE); | — |
Secondary
| Measure | Time frame |
|---|---|
| Barthel index; | — |
Countries
China
Contacts
Public ContactGuangcheng Ji
The Third Affiliated Clinical Hospital of Changchun University of Traditional Chinese Medicine
Outcome results
None listed