Ulcerative colitis
Conditions
Interventions
Group 1:usual care(mesalazine) + acupuncture
Group 2:usual care(mesalazine) + sham acupuncture
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Meet the diagnostic criteria for ulcerative colitis in the Expert Consensus Opinion (2022) on the diagnosis and treatment of ulcerative colitis in Chinese and Western medicine; 2) Patients with UC whose disease severity is mild or moderate in the active stage (Mayo score of 3~10); 3) Age =18 and =75 years old gender is not limited; 4) Those who voluntarily participated in this study and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with a combination of severe heart brain liver kidney and other diseases and malignant tumors; 2) Patients with previous or current diagnosis of schizophrenia moderate to severe depression and other psychotic disorders; 3) Patients with severe intestinal fistula abdominal abscess intestinal stenosis and intestinal obstruction gastrointestinal hemorrhage intestinal perforation and other complications; 4) Those who have participated in acupuncture clinical trials within 1 month before enrollment or are participating in other clinical trials; 5) Those who are unable to administer acupuncture treatment due to the presence of skin diseases limb disfigurement and other conditions in the area of acupoints selected for this study; 6) Patients who are in the period of preparation for pregnancy pregnancy and breastfeeding; 7)Patients with other diseases that may cause abdominal pain diarrhea and mucous-pus-blood stools such as bacillary dysentery amoebic dysentery and irritable bowel syndrome.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the clinical response rate at week 12; | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-1ß;the mucosal healing rate at week 12;Assessment of the efficacy of TCM symptoms;visual analogue scale(VAS);liver function;IL-10;TNF-a;Inflammatory Bowel Disease Questionnaire (IBDQ);Hospital Anxiety and Depress Scale(HADS);the clinical remission rate at week 12;Improved Mayo Single Score;IL-6; | — |
Countries
China
Contacts
Public ContactLu-Yi Wu
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Shanghai University of Traditional Chinese Medicine
Outcome results
None listed