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Percutaneous auricular vagus nerve stimulation in patients with AECOPD with gastrointestinal dysfunction

Percutaneous auricular vagus nerve stimulation in patients with AECOPD with gastrointestinal dysfunction

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025000050
Enrollment
Unknown
Registered
2025-01-09
Start date
2022-02-28
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute exacerbation of chronic obstructive pulmonary disease

Interventions

Experimental Group:On the basis of the usual clinical management protocols gua sha was performed in both ears for 30 minutes once in 3 days for a course of 3 treatments.
Contral Group:The usual clinical management plan was given - oral medication to suppress gastric acid, promote gastrointestinal motility, and aid digestion.

Sponsors

The First Hospital of Zhejiang University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 100 Years

Inclusion criteria

Inclusion criteria: (1) Developed according to the 2021 revised guidelines for the diagnosis and treatment of COPD by the Chronic Obstructive Pulmonary Disease Group of the Respiratory Diseases Branch of the Chinese Medical Association:. 1) with symptoms of chronic cough sputum and/or dyspnoea; ?? A history of exposure to risk factors such as smoking occupational dust and chemicals; ?? (iii) Excluding airflow limiting diseases with known etiology or characteristic pathological manifestations such as bronchiectasis fibrotic lesions of tuberculosis cystic fibrosis diffuse panbronchiolitis and occlusive bronchiolitis. ?? Laboratory tests: ?? 1) Lung function tests: the gold standard for diagnosing COPD. If FEV1/FVC is normal value ?? Gastrointestinal dysfunction can be diagnosed if at least 2 of the above indicators are met. ?? Translated with DeepL.com (free version) 1. Meet the above diagnostic criteria for AECOPD combined with gastrointestinal dysfunction; 2. Age =40 years old. 3. The patient has stopped using all the drugs that have influence on the function of gastrointestinal motility 1 week before the treatment; 4. No abnormality in fecal routine and fecal 0B in the last 1 month; 5. Informed consent: voluntary subjected to the test and signed an informed consent form and the informed consent process complied with ethical requirements.

Exclusion criteria

Exclusion criteria: 1. Patients in critical condition requiring endotracheal intubation and mechanical ventilation; 2. Acute gastrointestinal disease or surgery within the last 1 month; 3. Pregnant and lactating women; 4. Patients with combination of substantial abdominal mass hyperthyroidism serious primary diseases such as cardiovascular cerebrovascular hepatic renal and hematopoietic systems and psychiatric patients; 5. Those with ear skin breakage allergy and trauma; 6. Those who are participating in other clinical studies.

Design outcomes

Primary

MeasureTime frame
Gastrointestinal Symptoms Grading Scale;Criteria for the efficacy of Chinese medicine certificates;

Secondary

MeasureTime frame
Gastrointestinal hormone levels;

Countries

China

Contacts

Public ContactShengxi Chen

The First Hospital of Zhejiang University of Traditional Chinese Medicine

18005881510@189.cn+86 180 0588 1510

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026