Water Deficiency Type Dry Eye (Liver and Kidney Yin Deficiency Type)
Conditions
Interventions
control group:Hailu Eye Drops for Local Eye Drops
Test group:Zishui Hanmu needling method
Sponsors
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Those who meet the Western diagnostic criteria for dry eye caused by water deficiency and the traditional Chinese medicine diagnostic criteria for dry eye caused by liver and kidney yin deficiency (2) Patients aged 18 to 65, regardless of gender; (3) Informed and informed about this study, signed the informed consent form, voluntarily participated and cooperated with the participants of this trial (4) Not participated in any other drug clinical studies in the past 3 months
Exclusion criteria
Exclusion criteria: (1) Patients with severe systemic diseases such as heart, brain, liver, kidney, and blood system disorders, long-term use of anticoagulant drugs, and coagulation dysfunction; (2) Patients with Sjogren's syndrome; (3) Congenital absence of tears, absence of lacrimal glands, and neurological disorders (such as V and VII neuropathies, neuropathic keratitis, etc.); Obstruction of the lacrimal duct caused by extensive ocular surface damage (such as thermal or chemical eye burns, eyelid defects, ocular scar pemphigoid, etc.); Severe meibomian gland dysfunction and other active eye diseases (including acute ocular surface inflammation) affect clinical observers; Long term wearing of corneal contact lenses; (4) Recent history of eye surgery (including corneal refractive surgery, cataract surgery, etc.) or eye trauma; (5) Use systemic antihistamines, anticholinergic drugs, or other hormones that interfere with therapeutic efficacy in the past 3 months; (6) Individuals with mental illnesses, emotional stress, intellectual disabilities, or other conditions that are not suitable for clinical observation; (7) Sensitive constitution, known to be intolerant to the drugs used in this study; (8) Pregnant or lactating women, as well as patients with recent pregnancy plans; (9) Those who cannot persist in receiving treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chinese Dry Eye Questionnaire Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Non invasive tear film breakup time;fluorescein breakup time;tear meniscus height;Corneal fluorescein staining score;Quantitative scoring of traditional Chinese medicine symptoms; | — |
Countries
China
Contacts
Public ContactWei Dong
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed