Coronary heart failure
Conditions
Interventions
Control Group:Placebo
Experimental Group:Qishen Granule
Sponsors
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for chronic heart failure 2 .meet the diagnostic criteria of coronary heart disease 3 in line with the diagnostic criteria of pathogenic syndrome 4 LVEF=40% or NT-proBNP=450pg/ml 5. NYHA II-III level 6 age 18-75 years old 7. The respondents signed the informed consent to participate in the survey voluntarily.
Exclusion criteria
Exclusion criteria: 1. Acute phase of myocardial infarction (within 14 days) 2.combined with severe liver insufficiency (ALT>100U/L or AST>100U/L) severe renal insufficiency (glomerular filtration rate 5.5mmol/L) 3. Severe blood diseases and malignant tumors 4. Pregnant or lactating women 5. People with mental illness 6.serious heart failure life expectancy within six months 7. Those who have taken Chinese medicine or proprietary Chinese medicine with similar efficacy within the past week 8. Participate in other drug clinical researchers within one month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NT-proBNP;6minute walking test; | — |
Secondary
| Measure | Time frame |
|---|---|
| echocardiography;Classification of nyha heart function;Classification and quantification table of heart failure symptoms;Macro indicators of toxic pathogenic syndrome;The Kansas city cardiomyopathy questionnaire; | — |
Countries
China
Contacts
Public ContactLijing Zhang
Dongzhimen Hospital Affiliated to Beijing University of Chines
Outcome results
None listed