Severe Stroke with Paralytic Ileus
Conditions
Interventions
Acupuncture group :True acupuncture plus standard care
Sham acupuncture group:placebo acupuncture plus standard care
Sponsors
Zhongshan Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1) Meeting the diagnostic criteria for severe stroke with a Glasgow Coma Scale (GCS) score =12. 2) Clinically confirmed diagnosis of paralytic ileus, with enteral nutrition administered for more than 48 hours. 3) Age between 18 and 65 years (18 = age < 65), with no restriction on gender. 4) Relatively stable vital signs for at least 24 hours, with an APACHE II score <31. The patient or their legal representative has been informed about the study and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients with contraindications to acupuncture (e.g., severe skin diseases, bleeding disorders, etc.). 2) Patients with severe cardiac, hepatic, or renal dysfunction; severe electrolyte imbalance (e.g., hypokalemia); or other serious systemic diseases. 3) Pregnant or breastfeeding women. 4) Patients with a history of severe primary gastrointestinal diseases (e.g., inflammatory bowel disease, irritable bowel syndrome, gastrointestinal bleeding, gastrointestinal perforation, functional constipation) or a history of gastrointestinal surgery (e.g., gastrointestinal stoma, extensive gastrointestinal resection). 5) Patients in a state of persistent agitation or status epilepticus, unable to cooperate with the study or potentially affecting study outcomes. 6) Patients who have received laxatives (e.g., lactulose) or prokinetic agents (e.g., neostigmine) prior to the trial. 7) Patients with a history of probiotic use within the past two weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weekly Spontaneous Bowel Movements (WSBM); | — |
Secondary
| Measure | Time frame |
|---|---|
| Use of Rescue Medications;Assessment of Bowel Movement Regularity;Abdominal Circumference;Bowel Sounds;Glasgow Coma Scale (GCS);National Institutes of Health Stroke Scale (NIHSS);Modified Rankin Scale (mRS);Length of Hospitalization;omics biomarkers; | — |
Countries
China
Contacts
Public ContactLu Liming Jin Dan
Guangzhou University of Chinese Medicine
Outcome results
None listed