Helicobacter pylori-Related Halitosis
Conditions
Interventions
control group:Take Esomeprazole Enteric-coated Capsules (20mg bid) Amoxicillin Capsules (500mg bid) Clarithromycin Tablets (500mg bid) and Colloidal Bismuth Pectin Capsules (200mg bid) orally. Stop af
treatment group:Use "Qingyou Mouthwash" to rinse the mouth on the basis of the "Quadruple Therapy". It will be decocted uniformly on behalf of patients by Yixing Hospital of Traditional Chinese Medici
Sponsors
Yixing Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Meet the diagnostic criteria for Helicobacter pylori (Hp) infection; 2.Meet the diagnostic criteria for halitosis; 3.Meet the traditional Chinese medicine diagnostic criteria for the syndrome of dampness-heat in the spleen and stomach. 4.Have not previously received Hp eradication treatment; 5.Be aged between 18 and 65 with no gender restrictions; 6.Provide informed consent and voluntarily accept treatment.
Exclusion criteria
Exclusion criteria: 1.Patients who have used proton pump inhibitors (PPIs) within 2 weeks or antibiotics bismuth agents or other medications within 4 weeks; 2.Patients with oral diseases such as dental caries periodontitis or other oral diseases causing halitosis; 3.Patients with halitosis caused by upper respiratory tract infections with oral infections infections due to liver and biliary or urinary system diseases or halitosis due to poor lifestyle habits such as smoking and alcohol consumption; 4.Patients with allergic constitutions or known allergies to the drug components involved in this observation; 5.Patients with peptic ulcers gastric cancer or those who have undergone gastrointestinal surgery; 6.Patients with severe cardiopulmonary hepatic renal diseases and patients with mental illnesses; 7.Pregnant or breastfeeding women. Patients who meet any of the above criteria are not eligible to participate in this clinical observation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical efficacy evaluation of halitosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the Halitosis-related Quality of Life Test (HALT);Evaluation of the efficacy of Helicobacter pylori eradication;Changes in traditional Chinese medicine syndrome scores.; | — |
Countries
China
Contacts
Public ContactRuyi Ji
Yixing Traditional Chinese Medicine Hospital
Outcome results
None listed