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Clinical efficacy and mechanism of spleen-dampness-clearing gel against nausea and vomiting after endoscopic operation under general anesthesia based on transcriptome sequencing technology

Clinical efficacy and mechanism of spleen-dampness-clearing gel against nausea and vomiting after endoscopic operation under general anesthesia based on transcriptome sequencing technology

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000883
Enrollment
Unknown
Registered
2024-12-28
Start date
2024-05-09
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative nausea and vomiting

Interventions

test group:Homemade Chinese herbal ointment for acupoint application (bilateral Neiguan, Zusanli, Zhongwan)
control group:Blank control of acupoint application without ointment (bilateral Neiguan points and Zhusanli points and Zhongwan point)

Sponsors

Chongqing Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Surgical patients undergoing general anesthesia laparoscopy; 2. Chinese medicine diagnosis of damp-heat syndrome of spleen and stomach; 3. 18-65 years old; 4. ASA (American Society of Anesthesiologists graded before anesthesia according to the physical condition of the patient and the risk of the surgery) classification ?-?.

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to drugs; 2. Those with localized skin abnormalities at acupoints; 3. Those with serious abnormalities in liver and kidney functions

Design outcomes

Primary

MeasureTime frame
Incidence of postoperative nausea and vomiting;Transcriptome sequencing of serum samples;

Secondary

MeasureTime frame
Incidence of postoperative vomiting;Incidence of postoperative nausea;

Countries

China

Contacts

Public ContactShijie QU

Chongqing Traditional Chinese Medicine Hospital

176816664@qq.com13883177127

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026