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Clinical study on Central Sensitization mediated hyperalgesia of KOA treated by QuXiDianAnKouRou

Clinical study on Central Sensitization mediated hyperalgesia of KOA treated by QuXiDianAnKouRou

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000869
Enrollment
Unknown
Registered
2024-12-25
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee

Interventions

Conventional Tuina group:General Tuinauina
QuXiDianAnKouRou Group:the Tuina of QuXiDianAnKouRou
light touch group:light touch

Sponsors

Tianjin Academy of Traditional Chinese Medicine affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Meet the diagnostic criteria of KOA unilateral or bilateral onset and chronic pain as the main clinical symptoms; 2)Age 50-75 years old male or female; 3)K-L grade ?-? X-ray showed no large free body in the joint; 4) central sensitization inventory (CSI) score =40 5) did not have any related treatment within 1 week before participating in this clinical trial; 6) Patients and their families give informed consent and can cooperate in the assessment.

Exclusion criteria

Exclusion criteria: 1)Have undergone knee replacement surgery or other knee surgery 2)Knee pain caused by other diseases (such as autoimmune diseases infections malignant tumors trauma fractures serious fluid accumulation in joint muscles joint cavities lumbar spine diseases etc.) 3) Have undergone arthroscopy within the last 12 months or received intra-articular injections within the last 6 months 4) Serious acute and chronic organic diseases or mental illnesses 5) Have participated in other clinical trials within the past 3 months

Design outcomes

Primary

MeasureTime frame
The proportion of patients who achieved minimal clinically significant improvement;

Secondary

MeasureTime frame
Pain score;Inflammatory factor levels;Quality of life assessment;The proportion of patients who achieved minimal clinically significant improvement;Stiffness score;Functional score;Gait analysis;

Countries

China

Contacts

Public Contactyuliang

Tianjin Academy of Traditional Chinese Medicine affiliated Hospital

yuliangcxy@163.com13072281323

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026