chronic obstructive pulmonary disease
Conditions
Interventions
experimental group:Western medicine conventional treatment combined with Gu Ben Cough Granules
control group:Western medicine
Sponsors
The Third Affiliated Hospital of Zhejiang Chinese Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Meet the western medical diagnostic criteria for COPD in the stable stage E group; 2) Meet the diagnostic criteria for COPD in Chinese medicine deficiency of lung and kidney; 3) In the clinically stable stage of COPD no respiratory infections and AECOPD in the last 4 weeks; 4) 18 years old = age = 80 years old gender is not limited; 5) Voluntary acceptance of treatment. 5) Voluntarily accept the treatment and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients with airflow limitation due to asthma bronchiectasis pulmonary fibrosis; 2) Those who have undergone lung transplantation or lung resection; 3) Those who suffer from severe hypertension heart failure arrhythmia diabetes mellitus primary cardiac hepatic renal hematological and neurological symptoms etc. which are not under control; 4) Those who suffer from lung tumors malignant tumors (<5 years from the time of initial diagnosis or the presence of imaging or tumor markers and other tests to confirm the presence of recurrence metastasis or undergoing radiotherapy chemotherapy targeted therapy immunotherapy etc.); 5) Those who are allergic to known drug components; 6) Pregnant women women who are planning to be pregnant or breastfeeding; 7) Patients who are not considered suitable for enrollment by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragmatic ultrasound indices: diaphragm thickness (TDI) diaphragm mobility (DE) diaphragm inspiratory thickening fraction (TFdi) and diaphragm stiffness changes;Immune indicators (CD4+ CD8+ CD4+/CD8+); | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary Function Assessment(FEV1\FVC\FEV1/FVC);Self-assessment test for patients with chronic obstructive pulmonary disease;Chinese Medicine Score; | — |
Countries
China
Contacts
Public ContactLou LIming
Zhejiang Zhongshan Hospital
Outcome results
None listed