Colorectal cancer sarcopenia
Conditions
Interventions
experimental group:Oral Ginseng and Atractylodes Macrocephalae Soup
control subjects:No Ginseng and Atractylodis Macrocephalae.
Sponsors
Shanghai Tongren Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Postoperative pathology confirmed the diagnosis of colon cancer and supplemented with chemotherapy; 2) Meet the diagnostic criteria of postoperative chemotherapy XELOX program and spleen deficiency and dampness syndrome of colon cancer: primary symptoms: poor appetite tiredness fatigue gastrointestinal and abdominal distension or pain vomiting loose stools or diarrhea; secondary symptoms: yellowish color head and body drowsiness fatigue and laziness bland mouth and no thirst. Diagnosis can be made if there are two primary symptoms and one secondary symptom or one primary symptom and two secondary symptoms; 3) Meet the diagnostic criteria of sarcopenia: according to the latest diagnostic criteria of AWGS2019 muscle mass reduction is represented by ASMI <7.0kg/m2 for men and ASMI <5.7kg/m2 for women; muscle strength reduction is represented by grip strength <28kg for men and grip strength <18kg for women; and somatic function reduction is represented by 6m walking speed <1.0m/s. The diagnosis of sarcopenia can be fulfilled by a decrease in muscle mass with a decrease in muscle strength and/or a decrease in somatic function.
Exclusion criteria
Exclusion criteria: 1) preoperative radiotherapy or other immunotherapy etc.; 2) with heart liver kidney and other important organs failure. 2) Patients with heart liver kidney and other important organ failure; 3) Patients with physical deformities that cannot be tested for muscle strength or physical fitness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-meter walking speed;Muscle Strength;Appendicularskeletalmusclemass; | — |
Secondary
| Measure | Time frame |
|---|---|
| BMI;Body fat percentage; | — |
Countries
China
Contacts
Public ContactJin Huang
Shanghai Tongren Hospital
Outcome results
None listed