poor ovarian response
Conditions
Interventions
Placebo Control Group :Huyang Yangkun Formula Granules Placebo
Huyang Yangkun Formula Treatment Group :Huyang Yangkun Formula
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 43 Years
Inclusion criteria
Inclusion criteria: 1) Women aged = 43 years old; 2) Meets the diagnostic criteria for ovarian low response Poseidon 3 and 4 groups; 3) Meets the diagnostic criteria of traditional Chinese medicine; 4) Basic follicle stimulating hormone (FSH)<15mIU/ml 5) We plan to undergo 1-3 cycles of IVF or ICSI assisted reproductive treatment. 6) The patient agrees to conduct the study and signs an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Severe reproductive organ malformations such as congenital or acquired uterine dysplasia: monoangular uterus bicornuate uterus bicornuate uterus mediastinal uterus etc.; 2) Both or one of the spouses suffers from a genetic disease that is not suitable for reproduction as stipulated in the Maternal and Child Health Care Law; 3) Severe endometriosis adenomyosis immunological infertility intrauterine adhesions etc Merge reproductive system tumors thyroid dysfunction hyperprolactinemia etc.; 5) Male infertility non obstructive azoospermia or AZF gene microdeletion; 6) For those who are allergic to treatment drugs; 7) Patients with contraindications to assisted reproductive technology or pregnancy; 8) Long term follow-up cannot be conducted or compliance is poor or the researcher believes that there are any factors that affect the participants' participation in the trial or result evaluation; 9) Individuals who have participated in other clinical trials within the past 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total number of high-quality embryos in cases ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total number of retrieved eggs in the case, MII eggs in the case, normal fertilized eggs in the case, total number of available embryos in the case, number of implanted embryos in the case, and implantation rate in the case ;Detection of Chinese medicine active components in follicular fluid, detection of follicular fluid metabolism/lipidomics, detection of mitochondrial function in ovarian granulosae cells, detection of mitochondrial metabolism regulation genes ; | — |
Countries
China
Contacts
Public ContactHongyan Yang
Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed