Chronic nephritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for chronic nephritis with proteinuria as the main manifestation; 2. Aged between 18 and 75 years with no gender restrictions; 3. Urine protein quantification =3.5g/24h; 4.Using the CKD-EPI formula eGFR is calculated to be greater than 60 ml/min/1.73m². 5. Informed consent voluntary participation. The process of obtaining informed consent should comply with GCP regulations.
Exclusion criteria
Exclusion criteria: 1. Secondary chronic kidney disease including systemic lupus erythematosus hypertension-related kidney damage diabetic nephropathy gouty nephropathy and drug-induced nephropathy; 2. Patients with severe underlying diseases such as heart brain liver and lung diseases hematological disorders or malignant tumors and other debilitating diseases; 3. Acute renal failure or post-renal transplantation; 4. Patients currently receiving treatment with steroids or immunosuppressants; 5. Patients who cannot provide adequate informed consent due to intellectual or behavioral disabilities; 6. Patients with a history of alcohol or drug abuse; 7. Patients with severe mental disorders or those who are pregnant or breastfeeding; 8. Patients who are currently participating in other drug clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wind-evil syndrome score; | — |
Secondary
| Measure | Time frame |
|---|---|
| urine microprotein/urine creatinine serum;Serum creatinine;24-hour urine protein; | — |
Countries
China
Contacts
The Affiliated Hospital of Nanjing University of Traditional Chinese Medicine (Jiangsu Provincial Hospital of Traditional Chinese Medicine)