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Acupuncture intervention for gestational hypertension in the prevention and treatment of preeclampsia: a prospective multicenter open-label randomized controlled clinical trial

Acupuncture intervention for gestational hypertension in the prevention and treatment of preeclampsia: a prospective multicenter open-label randomized controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000818
Enrollment
Unknown
Registered
2024-12-13
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preeclampsia

Interventions

Acupuncture group:Acupuncture + labetalol
control group:labetalol

Sponsors

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Aged from 18 to 40 years old; 2 singleton live birth at 28-30 weeks of gestation; 3. Diagnosed with gestational hypertension; 4. sFlt-1/PLGF > 38; 5. Voluntarily participated in this study and signed informed consent

Exclusion criteria

Exclusion criteria: 1. Severe pregnancy-induced hypertension preeclampsia severe preeclampsia and eclampsia; 2. Patients with other serious primary diseases such as acute infectious diseases organic systemic diseases and malignant tumor diseases; 3. A history of hypertension and/or secondary causes of hypertension (such as underlying renal disease); 4. A fetus with a known genetic or chromosomal disorder; 5. Received acupuncture treatment within the past 3 months; 6. Received any antihypertensive drug treatment within the past 2 weeks; 7. Patients with known intentions to terminate pregnancy; 8. A history of alcohol or drug abuse within the past 6 months.

Design outcomes

Primary

MeasureTime frame
Incidence of preeclampsia;

Secondary

MeasureTime frame
Incidence of fetal growth restriction;ncidence of small for gestational age;Gestational age at delivery;Maternal mortality rate;Mean daily morning blood pressure;Serum sFlt-1 PLGF levels and sFlt-1/PLGF ratio before and after treatment;Incidence of low birth weight infants;Stillbirth rate;Incidence of placental abruption;Neonatal 1-minute Apgar score;Blood pressure immediately before and after acupuncture;

Countries

China

Contacts

Public ContactWu Linling

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

154384118@qq.com13642123194

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026