Parkinsons Disease
Conditions
Interventions
the treatment group:On the basis of anti-PD medication treatment with the Li-Lu-Gan-Cao-Fang
the control group:anti-PD medication treatment
Sponsors
Beijing Hospital of Integrated Traditional Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Patients who meet the Western medical diagnostic criteria for Parkinson's disease and the traditional Chinese medicine diagnostic criteria for tremor syndrome with wind-phlegm obstructing the orifices. 2.Patients aged between 50 and 85 years inclusive. 3.Patients with a modified Hoehn and Yahr (H&Y) scale score of =3. 4.Patients who have been on stable anti-parkinsonian medication for more than one month and are newly diagnosed with Parkinson's disease (PD). 5.Patients who are not currently taking TCM medications at the time of enrollment; if they have previously taken TCM medications they must have discontinued their use for at least one month or more. 6.Patients who voluntarily participate and provide informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with secondary parkinsonism syndrome. 2.Patients with significant comorbidities moderate to severe hepatic or renal dysfunction or severe infections. 3.Patients with a known allergy to the medications required for this trial. 4.Patients with moderate to severe dementia or psychiatric disorders that preclude effective communication. 5.Patients who have participated in other clinical drug trials within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 39-item Parkinson's disease questionnairePDQ-39;Unified Parkinson's disease rating scaleUPDRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Magnetic resonance spectroscopy;Traditional Chinese Medicine (TCM) Symptom Grading and Quantitative Scoring Standard for PD Patients;interleukin-6;Uric acid;Homocysteine; | — |
Countries
CHINA
Contacts
Public ContactHao wenjie
Beijing Hospital of Integrated Traditional Chinese and Western Medicine
Outcome results
None listed