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To investigate the effect mechanism of fire dragon cupping (Huo-Long-Guan) combined moxibustion on knee osteoarthritis based on NF-?B signaling pathway

To investigate the effect mechanism of fire dragon cupping (Huo-Long-Guan) combined moxibustion on knee osteoarthritis based on NF-?B signaling pathway

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2024000779
Enrollment
Unknown
Registered
2024-12-08
Start date
2024-12-18
Completion date
Unknown
Last updated
2025-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis,

Interventions

treatment group:fire dragon cupping (Huo-Long-Guan)
Waiting group:No treatment was given during the study period and the same treatment was given after the study

Sponsors

Qujing Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Age 50-70 gender unlimited; (2) Patients with unilateral KOA who meet the above Western diagnostic criteria have K-L grades 0-III; (3) According to the treatment plan can basically understand the research content cooperate with the clinical observation and follow-up of researchers and have good compliance; (4) The patient agrees to accept the treatment plan of this study and signs the informed consent which is subject to the study arranger.

Exclusion criteria

Exclusion criteria: (1) Women who are pregnant or breastfeeding; (2) Previous knee surgery history there are steel nails metal in the knee; (3) Patients with obvious deformity of knee joint; (4) long-term use of hormones or patients with metabolic bone disease; (5) Suspected or confirmed bone and joint tuberculosis or tumor patients; (6) Patients with severe cardiovascular respiratory brain liver kidney digestive system and mental diseases; (7) Allergic to moxa sticks or drugs with known ingredients used in the study; (8) Patients with skin rupture bleeding wounds; (9) Patients with osteoarthritis severe joint pain (VAS score =7) or joint swelling and skin temperature rise were still in the active stage.

Design outcomes

Primary

MeasureTime frame
WOMAC;effectiveness;

Secondary

MeasureTime frame
Serum NF-?B-related factor levels;Musculoskeletal ultrasound score;Lequesne;VAS;

Countries

China

Contacts

Public ContactChen Yanbei

Qujing Hospital of Traditional Chinese Medicine

497078641@qq.com18008849901

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026