Simple obesity, non-alcoholic fatty liver disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The actual body weight > 20% of the standard body weight; 2)BMI=28kg/m2; (3) The percentage of fat >30%; (4) The imaging findings of the liver met the diagnostic criteria for diffuse fatty liver and there was no other reason to explain it; (5) Exclude related diseases that can lead to fatty liver due to viral hepatitis, autoimmune liver disease, drug-induced liver injury, hereditary liver disease, etc.; (6) No previous alcohol history or milliliter equivalent ethanol content <140g/week (<70g/week for women); (7) Those who meet 2 of the first 3 of the above 6 items and meet the last 3 items at the same time can be diagnosed; (8) Age 18~60 years old; (9) Voluntarily participate in this trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Secondary obesity; (2) other methods of treatment for obese patients within 3 months; (3) Those who use other treatments or terminate treatment on their own; (4) Patients with obvious liver injury, serum aminotransferases > 2 times the upper limit of normal, and severe liver and kidney insufficiency; (5) Pregnant or lactating women; (6) Protein allergy; (7) Other conditions that the physician deems inappropriate for treatment; (8) Patients with cardiovascular and cerebrovascular diseases, mental abnormalities, blood diseases, tumors, and diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BMI(body mass index);Waist circumference;Waist-to-hip ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood lipids;TCM Symptom Points;PBF;Scores before and after liver ultrasound;TCM constitution assessment;Insulin resistance index; | — |
Countries
China
Contacts
PLA Naval Medical Center